BAY 55-9837 | Tocris Bioscience 2711/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

BAY 55-9837

catalog :

2711/1

quantity :

1 mg

price :

482 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Kittikulsuth W, Nakano D, Kitada K, Uyama T, Ueda N, Asano E, et al. Vasoactive intestinal peptide blockade suppresses tumor growth by regulating macrophage polarization and function in CT26 tumor-bearing mice. Sci Rep. 2023;13:927 pubmed publisher
Hamnett R, Crosby P, Chesham J, Hastings M. Vasoactive intestinal peptide controls the suprachiasmatic circadian clock network via ERK1/2 and DUSP4 signalling. Nat Commun. 2019;10:542 pubmed publisher
Pecoraro V, Sardone L, Chisari M, Licata F, Li Volsi G, Perciavalle V, et al. A subnanomolar concentration of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) pre-synaptically modulates glutamatergic transmission in the rat hippocampus acting through acetylcholine. Neuroscience. 2017;340:551-562 pubmed publisher
Toda A, Huganir R. Regulation of AMPA receptor phosphorylation by the neuropeptide PACAP38. Proc Natl Acad Sci U S A. 2015;112:6712-7 pubmed publisher
Pantazopoulos H, Dolatshad H, Davis F. Chronic stimulation of the hypothalamic vasoactive intestinal peptide receptor lengthens circadian period in mice and hamsters. Am J Physiol Regul Integr Comp Physiol. 2010;299:R379-85 pubmed publisher

image

image 1 :

Cat.No. 2711 - BAY 55-9837 His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Val-Ala-Ala-Lys-Lys-Tyr-Leu-Gln-Ser-Ile-Lys-Asn-Lys-Arg-Tyr-NH2 CAS No. 463930-25-8

product information

brand :

Tocris

MasterCode :

2711

SKU :

2711/1

product name :

BAY 55-9837

target :

VIP Receptor Agonists

category :

Peptides

unit size :

1 mg

purity :

95%

observed molecular weight :

3742.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Bay 55-9837 is a selective VPAC2 receptor agonist (EC50 values are 0.4, 100 and 1000 nM for VPAC2, VPAC1 and PAC1, respectively in a cAMP accumulation assay; IC50 values are 60, 8700 and 10000 nM for VPAC2, VPAC1 and PAC1, respectively in a competition binding assay). Stimulates glucose-dependent insulin secretion in isolated human pancreatic islets. Reduces HIV-1 viral replication and shows cooperative effects when given in conjunction with VPAC1 agonists.

extended description :

Potent and selective VPAC2 agonist

formula :

C 167 H 270 N 52 O 46

formula text :

C167H270N52O46

cas num :

463930-25-8

USD :

482 USD

product details :

Potent and selective VPAC2 agonist

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage