OGT 2115 | Tocris Bioscience 2710/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

OGT 2115

catalog :

2710/1

quantity :

1 mg (also 10 mg)

price :

97 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Whitehead M, McGonigal R, Willison H, Barnett S. Heparanase attenuates axon degeneration following sciatic nerve transection. Sci Rep. 2018;8:5219 pubmed publisher
Glasner D, Ratnasiri K, Puerta Guardo H, Espinosa D, Beatty P, Harris E. Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components. PLoS Pathog. 2017;13:e1006673 pubmed publisher
Changyaleket B, Chong Z, Dull R, Nanegrungsunk D, Xu H. Heparanase promotes neuroinflammatory response during subarachnoid hemorrhage in rats. J Neuroinflammation. 2017;14:137 pubmed publisher
Agelidis A, Hadigal S, Jaishankar D, Shukla D. Viral Activation of Heparanase Drives Pathogenesis of Herpes Simplex Virus-1. Cell Rep. 2017;20:439-450 pubmed publisher
Puerta Guardo H, Glasner D, Harris E. Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability. PLoS Pathog. 2016;12:e1005738 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2710

SKU :

2710/1

product name :

OGT 2115

description :

Antiangiogenic. Heparanase inhibitor

target :

Antiangiogenic Compounds

unit size :

1 mg (also 10 mg)

category :

Small Molecules

purity :

97%

storage :

Store at RT

observed molecular weight :

495.3

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

OGT 2115 is a heparanase inhibitor (IC50 = 0.4 M) that displays no major inhibition of human cytochrome P450 isoenzymes (IC50 30 M). Exhibits antiangiogenic properties in vitro (IC50 = 1 M).

product keywords :

Antiangiogenic Heparanase inhibitors inhibits Antiangiogenics Glycosylases Carbohydrate Metabolism OGT2115 Antiangiogenics Cell Adhesion Molecules Glycosylases 2710,

extended description :

Antiangiogenic. Heparanase inhibitor

chemical name text :

2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid

formula :

C24H16BrFN2O4

formula text :

C24H16BrFN2O4

cas num :

853929-59-6

USD :

USD 2025 :

97 USD

product details :

Antiangiogenic. Heparanase inhibitor

more info or order :

Tocris Bioscience product webpage