Liarozole dihydrochloride | Tocris Bioscience 2705 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Liarozole dihydrochloride

catalog :

2705

quantity :

10 mg (also 50 mg)

price :

197 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Bhattacharya N, Yuan R, Prestwood T, Penny H, DiMaio M, Reticker Flynn N, et al. Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer. Immunity. 2016;45:641-655 pubmed publisher
van de Bunt M, Lako M, Barrett A, Gloyn A, Hansson M, McCarthy M, et al. Insights into islet development and biology through characterization of a human iPSC-derived endocrine pancreas model. Islets. 2016;8:83-95 pubmed publisher
Thomas A, Henry J. Retinoic acid regulation by CYP26 in vertebrate lens regeneration. Dev Biol. 2014;386:291-301 pubmed publisher

product information

brand :

Tocris

master code :

2705

SKU :

2705/10

product name :

Liarozole dihydrochloride

description :

Blocks retinoic acid metabolism

target :

Additional Retinoic Acid Receptor Compounds

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

381.69

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cytochrome P450 inhibitor. Inhibits several cytochrome P450 enzymes including aromatase (CYP19) and retinoic acid 4-hydroxylase (CYP26). Blocks retinoic acid metabolism (retinoic acid metabolism blocking agent, RAMBA). Displays antitumor activity against androgen-dependent and independent rat prostate carcinomas.

catalog number base :

2705

extended description :

Blocks retinoic acid metabolism

chemical name text :

5-[(3-Chlorophenyl)-1H-imidazol-1-ylmethyl]-1H-benzimidazole dihydrochloride

formula :

C 17 H 13 ClN 4 .2HCl

formula text :

C17H13ClN4.2HCl

USD :

197 USD

alt names :

R-75251

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage