Carvedilol | Tocris Bioscience 2685 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Carvedilol

catalog :

2685

quantity :

50 mg

price :

102 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Zaytseva N, Lynn J, Wu Q, Mudaliar D, Sun H, Kuang P, et al. Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion. Sens Actuators B Chem. 2013;188: pubmed publisher
Baker J, Kemp P, March J, Fretwell L, Hill S, Gardiner S. Predicting in vivo cardiovascular properties of ?-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses. FASEB J. 2011;25:4486-97 pubmed publisher
Ajmo C, Collier L, Leonardo C, Hall A, Green S, Womble T, et al. Blockade of adrenoreceptors inhibits the splenic response to stroke. Exp Neurol. 2009;218:47-55 pubmed publisher

product information

brand :

Tocris

master code :

2685

SKU :

2685/50

product name :

Carvedilol

description :

Potent and non-selective antagonist; also potent 1 antagonist

target :

Non-selective Adrenergic beta Receptor Antagonists

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

406.47

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent -adrenoceptor and 1-adrenoceptor antagonist (Ki values are 0.81, 0.96 and 2.2 nM for 1-, 2- and 1-adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K+ (KIR) channels, voltage-dependent Ca2+ channels and exhibits antioxidant properties at higher concentrations.

catalog number base :

2685

extended description :

Potent and non-selective antagonist; also potent 1 antagonist

chemical name text :

1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

formula :

C 24 H 26 N 2 O 4

formula text :

C24H26N2O4

cas num :

72956-09-3

USD :

102 USD

alt names :

BM 14190

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage