Carvedilol | Tocris Bioscience 2685/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Carvedilol

catalog :

2685/50

quantity :

50 mg

price :

135 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Montoya A, Amaya C, Belmont A, Diab N, Trevino R, Villanueva G, et al. Use of non-selective β-blockers is associated with decreased tumor proliferative indices in early stage breast cancer. Oncotarget. 2017;8:6446-6460 pubmed publisher
Zaytseva N, Lynn J, Wu Q, Mudaliar D, Sun H, Kuang P, et al. Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion. Sens Actuators B Chem. 2013;188: pubmed publisher
Baker J, Kemp P, March J, Fretwell L, Hill S, Gardiner S. Predicting in vivo cardiovascular properties of ?-blockers from cellular assays: a quantitative comparison of cellular and cardiovascular pharmacological responses. FASEB J. 2011;25:4486-97 pubmed publisher
Ajmo C, Collier L, Leonardo C, Hall A, Green S, Womble T, et al. Blockade of adrenoreceptors inhibits the splenic response to stroke. Exp Neurol. 2009;218:47-55 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2685

SKU :

2685/50

product name :

Carvedilol

description :

Potent and non-selective antagonist; also potent 1 antagonist

target :

Non-selective Adrenergic beta Receptor Antagonists

unit size :

50 mg

category :

Small Molecules

purity :

98%

storage :

Store at +4°C

observed molecular weight :

406.47

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Carvedilol is a potent -adrenoceptor and 1-adrenoceptor antagonist (Ki values are 0.81, 0.96 and 2.2 nM for 1-, 2- and 1-adrenoceptors respectively) that displays antihypertensive and peripheral vasodilatory activity. Blocks cardiac inward-rectifier K+ (KIR) channels, voltage-dependent Ca2+ channels and exhibits antioxidant properties at higher concentrations.

product keywords :

-adrenoceptor beta-adrenoceptor b-adrenoceptor -adrenergic beta-adrenergic b-adrenergic 1-adrenoceptor alpha1-adrenoceptor a1-adrenoceptor a1-adrenergic antagonists Non-Selective Adrenoceptors BM14190 BM 14190 Non-selective Adrenergic Beta Receptors Adrenergic Alpha-1 Receptors 2685,

extended description :

Potent and non-selective antagonist; also potent 1 antagonist

chemical name text :

1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

formula :

C24H26N2O4

formula text :

C24H26N2O4

cas num :

72956-09-3

USD :

133

USD 2025 :

135 USD

product details :

Potent and non-selective antagonist; also potent 1 antagonist

alt names :

BM 14190

more info or order :

Tocris Bioscience product webpage