Sodium 4-Phenylbutyrate | Tocris Bioscience 2682 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Sodium 4-Phenylbutyrate

catalog :

2682

quantity :

100 mg

price :

102 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Myszor I, Parveen Z, Ottosson H, Bergman P, Agerberth B, Stromberg R, et al. Novel aroylated phenylenediamine compounds enhance antimicrobial defense and maintain airway epithelial barrier integrity. Sci Rep. 2019;9:7114 pubmed publisher
Karadottir H, Kulkarni N, Gudjonsson T, Karason S, Gudmundsson G. Cyclic mechanical stretch down-regulates cathelicidin antimicrobial peptide expression and activates a pro-inflammatory response in human bronchial epithelial cells. Peerj. 2015;3:e1483 pubmed publisher
Khan Z, Akhtar M, Ekström T. HDAC inhibitor 4-phenylbutyrate preserves immature phenotype of human embryonic midbrain stem cells: implications for the involvement of DNA methyltransferase. Int J Mol Med. 2011;28:977-83 pubmed publisher

product information

brand :

Tocris

master code :

2682

SKU :

2682/100

product name :

Sodium 4-Phenylbutyrate

description :

Histone deacetylase inhibitor

target :

Class I Histone Deacetylases Inhibitors

category :

Small Molecules

unit size :

100 mg

purity :

99%

observed molecular weight :

186.18

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Histone deacetylase inhibitor that displays anticancer activity. Inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. Also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of the -globin gene and affects hPPAR activation.

catalog number base :

2682

extended description :

Histone deacetylase inhibitor

chemical name text :

4-Phenylbutyric acid, sodium salt

formula :

C 10 H 11 NaO 2

formula text :

C10H11NaO2

cas num :

1716-12-7

USD :

102 USD

alt names :

4-PB, Sodium phenylbutyrate

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage