ZJ 43 | Tocris Bioscience 2675 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZJ 43

catalog :

2675

quantity :

10 mg

price :

304 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

2675

SKU :

2675/10

product name :

ZJ 43

description :

Glutamate carboxypeptidase II and III (NAALADase, NAAG peptidase) inhibitor

target :

Carboxypeptidase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

95%

observed molecular weight :

304.3

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent inhibitor of glutamate carboxypeptidase II and III (GCP II and III/NAAG peptidase/NAALADase) (Ki values are 0.8 and 23 nM respectively) that inhibits the hydrolysis of NAAG (IC50 = 2.4 nM) . Does not directly interact with NMDA or metabotropic glutamate receptors. Reduces neuronal degeneration in a rat model of traumatic brain injury (TBI) and reduces locomotor activity in the PCP-model of schizophrenia.

catalog number base :

2675

extended description :

Glutamate carboxypeptidase II and III (NAALADase, NAAG peptidase) inhibitor

chemical name text :

N-[[[(1S)-1-Carboxy-3-methylbutyl]amino]carbonyl]-L-glutamic acid

formula :

C 12 H 20 N 2 O 7

formula text :

C12H20N2O7

cas num :

723331-20-2

USD :

304 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage