JP 1302 dihydrochloride | Tocris Bioscience 2666/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

JP 1302 dihydrochloride

catalog :

2666/10

quantity :

10 mg (also 50 mg)

price :

292 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Jiang B, Wang F, Yang S, Fang P, Deng Z, Xiao J, et al. SKF83959 produces antidepressant effects in a chronic social defeat stress model of depression through BDNF-TrkB pathway. Int J Neuropsychopharmacol. 2014;18: pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2666

SKU :

2666/10

product name :

JP 1302 dihydrochloride

description :

Potent and selective 2C antagonist

target :

Adrenergic alpha-2 Receptor Antagonists

unit size :

10 mg (also 50 mg)

category :

Small Molecules

purity :

99%

storage :

Store at -20°C

observed molecular weight :

441.4

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

JP 1302 dihydrochloride is an 2C-adrenoceptor antagonist that displays ~ 50-fold selectivity over other 2-adrenoceptor subtypes (Ki values are 28, 1470, 1700 and 3150 nM for human 2C, 2B, 2D and 2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35GTP S binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo .

product keywords :

Potent selective 2C-adrenoceptor alpha2C-adrenoceptors 2c-adrenergic alpha2c-adrenergic a2c-adrenoceptor antagonists Receptors JP1302 dihydrochloride Adrenergic Alpha-2 Receptors 2666,

extended description :

Potent and selective 2C antagonist

chemical name text :

N-[4-(4-Methyl-1-piperazinyl)phenyl]-9-acridinamine dihydrochloride

formula :

C24H24N4.2HCl

formula text :

C24H24N4.2HCl

cas num :

1259314-65-2

USD :

289

USD 2025 :

292 USD

product details :

Potent and selective 2C antagonist

more info or order :

Tocris Bioscience product webpage