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company name :
Tocris Bioscience
product type :
chemical
product name :
BMS 191011
catalog :
2665/10
quantity :
10 mg (also 50 mg)
price :
226 USD
more info or order :
citations: 3
Reference
Shukla P, Ghatta S, Dubey N, Lemley C, Johnson M, Modgil A, et al. Maternal nutrient restriction during pregnancy impairs an endothelium-derived hyperpolarizing factor-like pathway in sheep fetal coronary arteries. Am J Physiol Heart Circ Physiol. 2014;307:H134-42 pubmed publisher
Martin J, Beriou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, et al. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid. Mucosal Immunol. 2014;7:101-13 pubmed publisher
Eroglu A, Hruszkewycz D, Dela Sena C, Narayanasamy S, Riedl K, Kopec R, et al. Naturally occurring eccentric cleavage products of provitamin A ?-carotene function as antagonists of retinoic acid receptors. J Biol Chem. 2012;287:15886-95 pubmed publisher
product information
brand :
Tocris, a Bio-Techne brand
catalog number base :
2665
SKU :
2665/10
product name :
BMS 191011
description :
Potent KCa1.1 (BK) channel opener
target :
Ca2+-Activated Potassium Channel Activators
unit size :
10 mg (also 50 mg)
category :
Small Molecules
purity :
98%
storage :
Store at RT
observed molecular weight :
370.71
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
BMS 191011 is a potent BKCa channel opener (large-conductance Ca2+-activated potassium channel, KCa1.1). Neuroprotectant in two distinct animal models of stroke (MCAO in the SHR rat and a normotensive model of focal stroke).
product keywords :
Potent Maxi-K channel openers BKCa KCa11 Potassium KCa Channels ca2+-activated ca2+-dependent K+ BMS191011 activators Ca2+-Activated Potassium Channels 2665,
extended description :
Potent KCa1.1 (BK) channel opener
chemical name text :
3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazol-2(3H)-one
formula :
C16H10ClF3N2O3
formula text :
C16H10ClF3N2O3
cas num :
202821-81-6
USD :
251
USD 2025 :
226 USD
product details :
Potent KCa1.1 (BK) channel opener
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK