Cabergoline | Tocris Bioscience 2664 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cabergoline

catalog :

2664

quantity :

10 mg (also 50 mg)

price :

224 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Leng Z, Lin S, Wu Z, Guo Y, Cai L, Shang H, et al. Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death. Autophagy. 2017;13:1404-1419 pubmed publisher
Gao Z, Cai L, Lu J, Wang C, Li Q, Chen J, et al. Expression of Stem Cell Markers and Dopamine D2 Receptors in Human and Rat Prolactinomas. Med Sci Monit. 2017;23:1827-1833 pubmed
Lin S, Leng Z, Guo Y, Cai L, Cai Y, Li N, et al. Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline. Oncotarget. 2015;6:39329-41 pubmed publisher
Odaka H, Numakawa T, Adachi N, Ooshima Y, Nakajima S, Katanuma Y, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS ONE. 2014;9:e99271 pubmed publisher

product information

brand :

Tocris

master code :

2664

SKU :

2664/10

product name :

Cabergoline

description :

D2-like agonist (D2>D3>D4)

target :

Non-selective Dopamine Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

451.6

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective D2-like dopamine receptor agonist (Ki values are 0.7, 1.5, 9.0 and 165 nM for D2, D3, D4 and D5 receptors respectively) that also displays high affinity for several serotonin receptor subtypes (Ki = 1.2 - 20.0 nM for 5-HT1A, 5-HT1D, 5-HT2A and 5-HT2B). Inhibits secretion of prolactin and growth hormone and reverses levodopa-induced dyskinesias in Parkinsonian monkeys.

catalog number base :

2664

extended description :

D2-like agonist (D2>D3>D4)

chemical name text :

N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)ergoline-8-carboxamide

formula :

C 26 H 37 N 5 O 2

formula text :

C26H37N5O2

cas num :

81409-90-7

USD :

224 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage