Cabergoline | Tocris Bioscience 2664/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cabergoline

catalog :

2664/10

quantity :

10 mg (also 50 mg)

price :

292 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Leng Z, Lin S, Wu Z, Guo Y, Cai L, Shang H, et al. Activation of DRD5 (dopamine receptor D5) inhibits tumor growth by autophagic cell death. Autophagy. 2017;13:1404-1419 pubmed publisher
Gao Z, Cai L, Lu J, Wang C, Li Q, Chen J, et al. Expression of Stem Cell Markers and Dopamine D2 Receptors in Human and Rat Prolactinomas. Med Sci Monit. 2017;23:1827-1833 pubmed
Lin S, Leng Z, Guo Y, Cai L, Cai Y, Li N, et al. Suppression of mTOR pathway and induction of autophagy-dependent cell death by cabergoline. Oncotarget. 2015;6:39329-41 pubmed publisher
Odaka H, Numakawa T, Adachi N, Ooshima Y, Nakajima S, Katanuma Y, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS ONE. 2014;9:e99271 pubmed publisher

product information

brand :

Tocris

catalog number base :

2664

SKU :

2664/10

product name :

Cabergoline

units size :

10 mg (also 50 mg)

description :

D2-like agonist (D2>D3>D4)

target :

Non-selective Dopamine Receptor Agonists

category :

Small Molecules

purity :

99%

observed molecular weight :

451.6

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cabergoline is a selective D2-like dopamine receptor agonist (Ki values are 0.7, 1.5, 9.0 and 165 nM for D2, D3, D4 and D5 receptors respectively) that also displays high affinity for several serotonin receptor subtypes (Ki = 1.2 - 20.0 nM for 5-HT1A, 5-HT1D, 5-HT2A and 5-HT2B). Inhibits secretion of prolactin and growth hormone and reverses levodopa -induced dyskinesias in Parkinsonian monkeys.

top caption :

D2-like agonist (D2>D3>D4)

extended description :

D2-like agonist (D2>D3>D4)

chemical name text :

N-[3-(Dimethylamino)propyl]-N-[(ethylamino)carbonyl]-6-(2-propenyl)ergoline-8-carboxamide

formula :

C26H37N5O2

formula text :

C26H37N5O2

cas num :

81409-90-7

USD :

292 USD

product details :

D2-like agonist (D2>D3>D4)

storage :

Store at +4Â°C

more info or order :

Tocris Bioscience product webpage