Concanamycin A | Tocris Bioscience 2656 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Concanamycin A

catalog :

2656

quantity :

10 ug

price :

154 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Gomes da Silva L, Jimenez A, Sauvat A, Xie W, Souquere S, Divoux S, et al. Recruitment of LC3 to damaged Golgi apparatus. Cell Death Differ. 2018;: pubmed publisher
Chabaud M, Heuzé M, Bretou M, Vargas P, Maiuri P, Solanes P, et al. Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nat Commun. 2015;6:7526 pubmed publisher

product information

brand :

Tocris

master code :

2656

SKU :

2656/10U

product name :

Concanamycin A

description :

H+-ATPase (vacuolar) inhibitor

target :

H+-ATPase Inhibitors

category :

Small Molecules

unit size :

10 ug

purity :

90%

observed molecular weight :

866.09

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Specific inhibitor of V-type (vacuolar) H+-ATPase that displays 2000-fold selectivity over other H+-ATPases (IC50 values are 9.2, 20000, 20000 and 20000 nM for yeast V-type, F-type, P-type H+-ATPases and porcine P-type Na+,K+-ATPase respectively). Blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines.

catalog number base :

2656

extended description :

H+-ATPase (vacuolar) inhibitor

chemical name text :

(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy- -D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-

formula :

C 46 H 75 NO 14

formula text :

C46H75NO14

cas num :

80890-47-7

USD :

154 USD

alt names :

Folimycin

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage