Concanamycin A | Tocris Bioscience 2656/100U product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Concanamycin A

catalog :

2656/100U

quantity :

100 ug

price :

205 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Nagaoka T, Furuse M, Ohtsuka T, Tsuchida K, Kishi M. Vangl2 interaction plays a role in the proteasomal degradation of Prickle2. Sci Rep. 2019;9:2912 pubmed publisher
Gomes da Silva L, Jimenez A, Sauvat A, Xie W, Souquere S, Divoux S, et al. Recruitment of LC3 to damaged Golgi apparatus. Cell Death Differ. 2018;: pubmed publisher
Chabaud M, Heuzé M, Bretou M, Vargas P, Maiuri P, Solanes P, et al. Cell migration and antigen capture are antagonistic processes coupled by myosin II in dendritic cells. Nat Commun. 2015;6:7526 pubmed publisher
Tel J, Smits E, Anguille S, Joshi R, Figdor C, de Vries I. Human plasmacytoid dendritic cells are equipped with antigen-presenting and tumoricidal capacities. Blood. 2012;120:3936-44 pubmed publisher

product information

brand :

Tocris

catalog number base :

2656

SKU :

2656/100U

product name :

Concanamycin A

units size :

100 ug

description :

H+-ATPase (vacuolar) inhibitor

target :

H+-ATPase Inhibitors

category :

Small Molecules

purity :

90%

observed molecular weight :

866.09

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Concanamycin A is a specific inhibitor of V-type (vacuolar) H+-ATPase that displays 2000-fold selectivity over other H+-ATPases (IC50 values are 9.2, 20000, 20000 and 20000 nM for yeast V-type, F-type, P-type H+-ATPases and porcine P-type Na+,K+-ATPase respectively). Blocks cell surface expression of virus envelope glycoproteins without affecting synthesis and exhibits cytotoxicity in several cell lines.

top caption :

H+-ATPase (vacuolar) inhibitor

extended description :

H+-ATPase (vacuolar) inhibitor

chemical name text :

(3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(Aminocarbonyl)-2,6-dideoxy- -D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-9-ethyl-8,10-dihydroxy-

formula :

C46H75NO14

formula text :

C46H75NO14

cas num :

80890-47-7

USD :

205 USD

product details :

H+-ATPase (vacuolar) inhibitor

alt names :

Folimycin

storage :

Store at -20Â°C

more info or order :

Tocris Bioscience product webpage