GW 9508 | Tocris Bioscience 2649 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GW 9508

catalog :

2649

quantity :

10 mg (also 50 mg)

price :

166 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Dragano N, Solon C, Ramalho A, de Moura R, Razolli D, Christiansen E, et al. Polyunsaturated fatty acid receptors, GPR40 and GPR120, are expressed in the hypothalamus and control energy homeostasis and inflammation. J Neuroinflammation. 2017;14:91 pubmed publisher
Watson S, Brown A, Holliday N. Differential signaling by splice variants of the human free fatty acid receptor GPR120. Mol Pharmacol. 2012;81:631-42 pubmed publisher
Oh D, Talukdar S, Bae E, Imamura T, Morinaga H, Fan W, et al. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 2010;142:687-98 pubmed publisher

product information

brand :

Tocris

master code :

2649

SKU :

2649/10

product name :

GW 9508

description :

Potent and selective FFA1 (GPR40) agonist

target :

Free Fatty Acid Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

347.41

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent and selective agonist for the free fatty acid receptor FFA1 (GPR40) (pEC50 values are 7.32, 4.3 and 4.3 for FFA1, FFA2 and FFA3 receptors respectively). Inactive against a range of other GPCRs, kinases, proteases, integrins and PPARs. Potentiates glucose-stimulated insulin secretion in MIN6 cells (pEC50 = 6.14).

catalog number base :

2649

extended description :

Potent and selective FFA1 (GPR40) agonist

chemical name text :

4-[[(3-Phenoxyphenyl)methyl]amino]benzenepropanoic acid

formula :

C 22 H 21 NO 3

formula text :

C22H21NO3

cas num :

885101-89-3

USD :

166 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage