product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NSC 632839 hydrochloride
catalog :
2647
quantity :
10 mg (also 50 mg)
price :
126 USD
more info or order :
citations: 2
Reference
Ryals M, Morell R, Martin D, Boger E, Wu P, Raible D, et al. The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity. Front Cell Neurosci. 2018;12:445 pubmed publisher
Zeng M, Ren L, Mizuno K, Nestoras K, Wang H, Tang Z, et al. CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection. Nat Commun. 2016;7:11364 pubmed publisher
product information
brand :
Tocris
master code :
2647
SKU :
2647/10
product name :
NSC 632839 hydrochloride
description :
Inhibitor of ubiquitin isopeptidase activity
target :
Deubiquitinating Enzyme Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
99%
species :
Multi-Species
observed molecular weight :
339.86
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Inhibitor of ubiquitin isopeptidase activity that displays no effect on the proteolytic activity of the proteasome. Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 values are 15.65 and 16.23 u M in E1A and E1A/C9CN cells respectively).
catalog number base :
2647
extended description :
Inhibitor of ubiquitin isopeptidase activity
chemical name text :
3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
formula :
C 21 H 21 NO.HCl
formula text :
C21H21NO.HCl
cas num :
157654-67-6
USD :
126 USD
alt names :
F6
storage :
Store at +4°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK