This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
NSC 632839 hydrochloride
catalog :
2647/10
quantity :
10 mg
price :
142 USD
citations: 2
Reference
Ryals M, Morell R, Martin D, Boger E, Wu P, Raible D, et al. The Inner Ear Heat Shock Transcriptional Signature Identifies Compounds That Protect Against Aminoglycoside Ototoxicity. Front Cell Neurosci. 2018;12:445 pubmed publisher
Zeng M, Ren L, Mizuno K, Nestoras K, Wang H, Tang Z, et al. CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection. Nat Commun. 2016;7:11364 pubmed publisher
product information
brand :
Tocris
master code :
2647
SKU :
2647/10
product name :
NSC 632839 hydrochloride
unit size :
10 mg
description :
Potent and selective FFA1 (GPR40) agonist
target :
Deubiquitinating Enzyme Inhibitors
category :
Small Molecules
alt names :
F6
purity :
99%
species :
Multi-Species
storage :
Store at +4°C
observed molecular weight :
339.86
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
NSC 632839 hydrochloride is an inhibitor of ubiquitin isopeptidase activity that displays no effect on the proteolytic activity of the proteasome. Induces apoptosis via a Bcl-2-dependent and apoptosome-independent pathway of caspase activation (IC50 values are 15.65 and 16.23 u M in E1A and E1A/C9CN cells respectively).
extended description :
Inhibitor of ubiquitin isopeptidase activity
chemical name text :
3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride
formula :
C 21 H 21 NO.HCl
formula text :
C21H21NO.HCl
cas num :
157654-67-6
USD :
137
Jul-22 :
142 USD
product details :
Inhibitor of ubiquitin isopeptidase activity
sizes available :
10 mg (also 50 mg)
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK