NGB 2904 | Tocris Bioscience 2635/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

NGB 2904

catalog :

2635/10

quantity :

10 mg (also 50 mg)

price :

251 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Nagata M, Yokooji T, Nakai T, Miura Y, Tomita T, Taogoshi T, et al. Blockade of multiple monoamines receptors reduce insulin secretion from pancreatic β-cells. Sci Rep. 2019;9:16438 pubmed publisher
Axel A, Mikkelsen J, Hansen H. Tesofensine, a novel triple monoamine reuptake inhibitor, induces appetite suppression by indirect stimulation of alpha1 adrenoceptor and dopamine D1 receptor pathways in the diet-induced obese rat. Neuropsychopharmacology. 2010;35:1464-76 pubmed publisher

image

image 1 :

Cat.No. 2635 - NGB 2904 C28H29Cl2N3O.HCl CAS No. 189061-11-8

product information

brand :

Tocris

master code :

2635

SKU :

2635/10

product name :

NGB 2904

description :

Potent and selective D3 antagonist

target :

Dopamine D3 Receptor Antagonists

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

530.92

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NGB 2904 is a potent and selective dopamine D3 receptor antagonist (Ki values are 1.4, 217, 223, 642, 5000, 10000 and 10000 nM for D3, D2, 5-HT2, 1, D4, D1 and D5 receptors respectively). Potently antagonizes quinpirole -stimulated mitogenesis (IC50 = 6.8 nM). Attenuates cocaine s rewarding effects and inhibits relapse to drug-seeking behavior.

extended description :

Potent and selective D3 antagonist

chemical name text :

N-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butyl]-9H-fluorene-2-carboxamide

formula :

C 28 H 29 Cl 2 N 3 O.HCl

formula text :

C28H29Cl2N3O.HCl

cas num :

189061-11-8

USD :

239

USD 2023 :

251 USD

product details :

Potent and selective D3 antagonist

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage