CL 82198 hydrochloride | Tocris Bioscience 2632/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CL 82198 hydrochloride

catalog :

2632/10

quantity :

10 mg (also 50 mg)

price :

184 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Lisse T, Middleton L, Pellegrini A, Martin P, Spaulding E, Lopes O, et al. Paclitaxel-induced epithelial damage and ectopic MMP-13 expression promotes neurotoxicity in zebrafish. Proc Natl Acad Sci U S A. 2016;113:E2189-98 pubmed publisher
Wang M, Sampson E, Jin H, Li J, Ke Q, Im H, et al. MMP13 is a critical target gene during the progression of osteoarthritis. Arthritis Res Ther. 2013;15:R5 pubmed publisher
Meierjohann S, Hufnagel A, Wende E, Kleinschmidt M, Wolf K, Friedl P, et al. MMP13 mediates cell cycle progression in melanocytes and melanoma cells: in vitro studies of migration and proliferation. Mol Cancer. 2010;9:201 pubmed publisher

image

image 1 :

Cat.No. 2632 - CL 82198 hydrochloride C17H23N2O3.HCl CAS No. 1188890-36-9

product information

brand :

Tocris

master code :

2632

SKU :

2632/10

product name :

CL 82198 hydrochloride

description :

Selective inhibitor of MMP-13

target :

Synthetic Metalloprotease Inhibitors

category :

Small Molecules

sizes available :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

338.83

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CL 82198 hydrochloride is a selective inhibitor of MMP-13 (89% inhibition at 10 u g/mL) that displays no activity at MMP-1, MMP-9 or TACE. Inhibits in vitro invasion by the human pituitary adenoma cell line HP75. Rescues paclitaxel induced axon degradation and reduces associated neurotoxicity in zebrafish.

extended description :

Selective inhibitor of MMP-13

chemical name text :

N-[4-(4-Morpholinyl)butyl]-2-benzofurancarboxamide hydrochloride

formula :

C 17 H 23 N 2 O 3 .HCl

formula text :

C17H23N2O3.HCl

cas num :

1188890-36-9

USD :

175

USD 2023 :

184 USD

product details :

Selective inhibitor of MMP-13

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage