product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Oxaliplatin
catalog :
2623/50
quantity :
50 mg
price :
202 USD
more info or order :
Tocris Bioscience product webpage
citations: 7
Reference
Massey A. Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC. PLoS ONE. 2015;10:e0134306 pubmed publisher
Fukushima K, Tsuchiya K, Kano Y, Horita N, Hibiya S, Hayashi R, et al. Atonal homolog 1 protein stabilized by tumor necrosis factor α induces high malignant potential in colon cancer cell line. Cancer Sci. 2015;106:1000-7 pubmed publisher
Li N, Lorenzi F, Kalakouti E, Normatova M, Babaei Jadidi R, Tomlinson I, et al. FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15. Oncotarget. 2015;6:9240-56 pubmed
Bryant C, Rawlinson R, Massey A. Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers. BMC Cancer. 2014;14:570 pubmed publisher
Rawlinson R, Massey A. ?H2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments. BMC Cancer. 2014;14:483 pubmed publisher
Ibáñez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, et al. A high throughput scintillation proximity imaging assay for protein methyltransferases. Comb Chem High Throughput Screen. 2012;15:359-71 pubmed
Boyette Davis J, Dougherty P. Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline. Exp Neurol. 2011;229:353-7 pubmed publisher
product information
brand :
Tocris
catalog number base :
2623
SKU :
2623/50
product name :
Oxaliplatin
units size :
50 mg
description :
DNA cross-linking antitumor agent
target :
Apoptosis Inducer Compounds
category :
Small Molecules
purity :
98%
observed molecular weight :
397.29
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
review stars :
5
details of functionality :
Oxaliplatin is an antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance.
top caption :
DNA cross-linking antitumor agent
extended description :
DNA cross-linking antitumor agent
chemical name text :
Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II)
formula :
C8H14N2O4Pt
formula text :
C8H14N2O4Pt
cas num :
61825-94-3
USD :
202 USD
product details :
DNA cross-linking antitumor agent
alt names :
Eloxatin
storage :
Store at +4°C
more info or order :
Tocris Bioscience product webpage
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK