Oxaliplatin | Tocris Bioscience 2623/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Oxaliplatin

catalog :

2623/50

quantity :

50 mg

price :

202 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Massey A. Multiparametric Cell Cycle Analysis Using the Operetta High-Content Imager and Harmony Software with PhenoLOGIC. PLoS ONE. 2015;10:e0134306 pubmed publisher
Fukushima K, Tsuchiya K, Kano Y, Horita N, Hibiya S, Hayashi R, et al. Atonal homolog 1 protein stabilized by tumor necrosis factor Î± induces high malignant potential in colon cancer cell line. Cancer Sci. 2015;106:1000-7 pubmed publisher
Li N, Lorenzi F, Kalakouti E, Normatova M, Babaei Jadidi R, Tomlinson I, et al. FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15. Oncotarget. 2015;6:9240-56 pubmed
Bryant C, Rawlinson R, Massey A. Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers. BMC Cancer. 2014;14:570 pubmed publisher
Rawlinson R, Massey A. ?H2AX and Chk1 phosphorylation as predictive pharmacodynamic biomarkers of Chk1 inhibitor-chemotherapy combination treatments. BMC Cancer. 2014;14:483 pubmed publisher
Ibáñez G, Shum D, Blum G, Bhinder B, Radu C, Antczak C, et al. A high throughput scintillation proximity imaging assay for protein methyltransferases. Comb Chem High Throughput Screen. 2012;15:359-71 pubmed
Boyette Davis J, Dougherty P. Protection against oxaliplatin-induced mechanical hyperalgesia and intraepidermal nerve fiber loss by minocycline. Exp Neurol. 2011;229:353-7 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2623

SKU :

2623/50

product name :

Oxaliplatin

description :

DNA cross-linking antitumor agent

target :

Apoptosis Inducer Compounds

unit size :

50 mg

category :

Small Molecules

purity :

99%

storage :

Store at +4°C

observed molecular weight :

397.29

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Oxaliplatin is an antitumor agent that forms platinum-DNA adducts. Causes intra- and interstrand DNA crosslinks blocking DNA replication and transcription. Displays higher cytotoxicity and lower nephrotoxicity than analog cisplatin (Cat. No. 2251) and shows antitumor activity in cell lines with acquired cisplatin resistance.

product keywords :

DNA cross-linking antitumor agent inhibitors inhibits synthesis Apoptosis Inducers platinum-DNA adducts chemotherapeutics Eloxatin Apoptosis Inducers DNA, RNA and Protein Synthesis 2623,

extended description :

DNA cross-linking antitumor agent

chemical name text :

Oxalato[(1R-trans)-1,2-cyclohexanediamine]platinum(II)

formula :

C8H14N2O4Pt

formula text :

C8H14N2O4Pt

cas num :

61825-94-3

USD :

193

USD 2025 :

202 USD

product details :

DNA cross-linking antitumor agent

alt names :

Eloxatin

more info or order :

Tocris Bioscience product webpage