ARP 100 | Tocris Bioscience 2621 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ARP 100

catalog :

2621

quantity :

5 mg

price :

144 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Ji J, Jia S, Jia Y, Ji K, Hargest R, Jiang W. WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-Î³ pathways. Br J Cancer. 2015;113:921-33 pubmed publisher
Hensley H, Roder N, O Brien S, Bickel L, Xiao F, Litwin S, et al. Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice. Neoplasia. 2012;14:451-62 pubmed
Chetty C, Lakka S, Bhoopathi P, Rao J. MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells. Int J Cancer. 2010;127:1081-95 pubmed publisher

product information

brand :

Tocris

master code :

2621

SKU :

2621/5

product name :

ARP 100

description :

Selective inhibitor of MMP-2

target :

Synthetic Metalloprotease Inhibitors

category :

Small Molecules

unit size :

5 mg

purity :

99%

observed molecular weight :

364.42

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective inhibitor of MMP-2 (IC50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC50 values are 200, 4500, 50000 and 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.

catalog number base :

2621

extended description :

Selective inhibitor of MMP-2

chemical name text :

2-[((1,1 -Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide

formula :

C 17 H 20 N 2 O 5 S

formula text :

C17H20N2O5S

cas num :

704888-90-4

USD :

144 USD

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage