This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
ARP 100
catalog :
2621/5
quantity :
5 mg
price :
173 USD
citations: 3
Reference
Ji J, Jia S, Jia Y, Ji K, Hargest R, Jiang W. WISP-2 in human gastric cancer and its potential metastatic suppressor role in gastric cancer cells mediated by JNK and PLC-γ pathways. Br J Cancer. 2015;113:921-33 pubmed publisher
Hensley H, Roder N, O Brien S, Bickel L, Xiao F, Litwin S, et al. Combined in vivo molecular and anatomic imaging for detection of ovarian carcinoma-associated protease activity and integrin expression in mice. Neoplasia. 2012;14:451-62 pubmed
Chetty C, Lakka S, Bhoopathi P, Rao J. MMP-2 alters VEGF expression via alphaVbeta3 integrin-mediated PI3K/AKT signaling in A549 lung cancer cells. Int J Cancer. 2010;127:1081-95 pubmed publisher
product information
brand :
Tocris
master code :
2621
SKU :
2621/5
rank :
0.061
product name :
ARP 100
description :
Selective inhibitor of MMP-2
target :
Synthetic Metalloprotease Inhibitors
category :
Small Molecules
sizes available :
5 mg
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ARP 100 is a selective inhibitor of MMP-2 (IC50 = 12 nM); displays selectivity over MMP-9, MMP-3, MMP-1 and MMP-7 (IC50 values are 200, 4500, 50000 and 50000 nM respectively). Exhibits anti-invasive properties in HT1080 fibrosarcoma cells.
extended description :
Selective inhibitor of MMP-2
chemical name text :
2-[((1,1 -Biphenyl)-4-ylsulfonyl)-(1-methylethoxy)amino]-N-hydroxyacetamide
formula :
C 17 H 20 N 2 O 5 S
formula text :
C17H20N2O5S
cas num :
704888-90-4
USD :
173 USD
product details :
Selective inhibitor of MMP-2
storage :
Store the unopened product at 2 - 8 °C. Do not use past expiration date.
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK