Ryuvidine | Tocris Bioscience 2609 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ryuvidine

catalog :

2609

quantity :

10 mg (also 50 mg)

price :

210 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
FitzGerald J, Murillo L, O Brien G, O Connell E, O Connor A, Wu K, et al. A high through-put screen for small molecules modulating MCM2 phosphorylation identifies Ryuvidine as an inducer of the DNA damage response. PLoS ONE. 2014;9:e98891 pubmed publisher

product information

brand :

Tocris

master code :

2609

SKU :

2609/10

product name :

Ryuvidine

description :

SETD8 inhibitor; also CDK4 inhibitor

target :

Lysine Methyltransferase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

284.33

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of SETD8 protein lysine methyltransferase (PKMT) (IC50 = 0.5 M); suppresses H4K20 monomethylation in vitro . Also inhibits cyclin-dependent kinase (CDK) 4 (IC50 = 6.0 u M at CDK4/cyclin D1). Induces S phase accumulation in HEK293T cells. Cytotoxic against a range of human cancer cells.

catalog number base :

2609

product keywords :

Cyclin-dependent protein kinase 4 cdk4 inhibitors SETD8 protein lysine methyltransferases inhibits SPS8I2 Cyclin-dependent Kinase Lysine Methyltransferases Other Lysine Methyltransferases 2609,

extended description :

SETD8 inhibitor; also CDK4 inhibitor

chemical name text :

2-Methyl-5-[(4-methylphenyl)amino]-4,7-benzothiazoledione

formula :

C 15 H 12 N 2 O 2 S

formula text :

C15H12N2O2S

cas num :

265312-55-8

2020 USD :

203

2021 USD :

210 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage