PD 144418 oxalate | Tocris Bioscience 2606/50 product information

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product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PD 144418 oxalate

catalog :

2606/50

quantity :

50 mg

price :

814 USD

citations: 2

Reference
Sánchez Blázquez P, Cortés Montero E, Rodríguez Muñoz M, Garzón J. Sigma 1 Receptor Antagonists Inhibit Manic-Like Behaviors in Two Congenital Strains of Mice. Int J Neuropsychopharmacol. 2018;21:938-948 pubmed publisher
Navarro G, Quiroz C, Moreno Delgado D, Sierakowiak A, McDowell K, Moreno E, et al. Orexin-corticotropin-releasing factor receptor heteromers in the ventral tegmental area as targets for cocaine. J Neurosci. 2015;35:6639-53 pubmed publisher

product information

brand :

Tocris

master code :

2606

SKU :

2606/50

product name :

PD 144418 oxalate

description :

High affinity, selective 1 ligand

target :

Sigma1 Receptor Ligands

category :

Small Molecules

unit size :

50 mg

purity :

98%

observed molecular weight :

372.42

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PD 144418 oxalate is a high affinity, selective 1 ligand (Ki values are 0.08 and 1377 nM for 1 and 2 respectively). Displays no significant activity at a wide range of other receptors, ion channels and enzymes. Antagonizes mescaline-induced scratching in mice following i.p. administration. Also attenuates cocaine-induced hyperactivity in mice.

catalog number base :

2606

extended description :

High affinity, selective 1 ligand

chemical name text :

1,2,3,6-Tetrahydro-5-[3-(4-methylphenyl)-5-isoxazolyl]-1-propylpyridine oxalate

formula :

C 18 H 22 N 2 O.C 2 H 2 O 4

formula text :

C18H22N2O.C2H2O4

cas num :

1794760-28-3

USD 2021 :

794

USD 2022 :

814 USD

product details :

High affinity, selective 1 ligand

storage :

Desiccate at RT