Mexiletine hydrochloride | Tocris Bioscience 2596 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Mexiletine hydrochloride

catalog :

2596

quantity :

50 mg

price :

83 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Rojas F, Gonzalez D, Cortes N, Ampuero E, HernÃ¡ndez D, Fritz E, et al. Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Front Cell Neurosci. 2015;9:203 pubmed publisher
Rojas F, Cortes N, Abarzúa S, Dyrda A, van Zundert B. Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress. Front Cell Neurosci. 2014;8:24 pubmed publisher

product information

brand :

Tocris

master code :

2596

SKU :

2596/50

product name :

Mexiletine hydrochloride

description :

Na+ channel blocker; antiarrhythmic agent

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

215.72

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Use-dependent sodium channel blocker (IC50 values are 75.3 and 23.6 u M for tonic and use-dependent block respectively). Class Ib antiarrhythmic, neuroprotective and antimyotonic agent.

catalog number base :

2596

product keywords :

Na+ channel blockers antiarrhythmic agent Sodium NaV Channels voltage-gated voltage-dependent Ko1173 Ko 1173 Voltage-gated Sodium Channels 2596,

extended description :

Na+ channel blocker; antiarrhythmic agent

chemical name text :

1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride

formula :

C 11 H 17 NO.HCl

formula text :

C11H17NO.HCl

cas num :

1/4/70

2020 USD :

2021 USD :

83 USD

alt names :

Ko 1173

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage