2596/50 | Tocris Bioscience 2596/50 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

2596/50

catalog :

2596/50

quantity :

50 mg

price :

106 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Rojas F, Gonzalez D, Cortes N, Ampuero E, HernÃ¡ndez D, Fritz E, et al. Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. Front Cell Neurosci. 2015;9:203 pubmed publisher
Rojas F, Cortes N, Abarzúa S, Dyrda A, van Zundert B. Astrocytes expressing mutant SOD1 and TDP43 trigger motoneuron death that is mediated via sodium channels and nitroxidative stress. Front Cell Neurosci. 2014;8:24 pubmed publisher

image

image 1 :

Cat.No. 2596 - Mexiletine hydrochloride C11H17NO.HCl CAS No. 5370-01-4

product information

master code :

2596

SKU :

2596/50

product name :

Mexiletine hydrochloride

unit size :

50 mg

description :

Na+ channel blocker; antiarrhythmic agent

target :

Voltage-gated Sodium Channel Blockers

category :

Small Molecules

purity :

99%

observed molecular weight :

215.72

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Mexiletine hydrochloride is an use-dependent sodium channel blocker (IC50 values are 75.3 and 23.6 u M for tonic and use-dependent block respectively). Class Ib antiarrhythmic, neuroprotective and antimyotonic agent.

top caption :

Na+ channel blocker; antiarrhythmic agent

extended description :

Na+ channel blocker; antiarrhythmic agent

chemical name text :

1-(2,6-Dimethylphenoxy)-2-propanamine hydrochloride

formula :

C11H17NO.HCl

formula text :

C11H17NO.HCl

cas num :

1/4/70

USD :

106 USD

product details :

Na+ channel blocker; antiarrhythmic agent

alt names :

Ko 1173

storage :

Desiccate at +4░C

more info or order :

Tocris Bioscience product webpage