Compstatin | Tocris Bioscience 2585 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Compstatin

catalog :

2585

quantity :

1 mg

price :

235 USD

more info or order :

Tocris Bioscience product webpage

citations: 6

Reference
Koupenova M, Corkrey H, Vitseva O, Manni G, Pang C, Clancy L, et al. The role of platelets in mediating a response to human influenza infection. Nat Commun. 2019;10:1780 pubmed publisher
Larsen M, Quintana M, Ditlev S, Bayarri Olmos R, Ofori M, Hviid L, et al. Evasion of Classical Complement Pathway Activation on Plasmodium falciparum-Infected Erythrocytes Opsonized by PfEMP1-Specific IgG. Front Immunol. 2018;9:3088 pubmed publisher
Lee D, Yi T, Lee H, Kim S, Park S, Jeon M, et al. Mesenchymal stem cells infected with Mycoplasma arginini secrete complement C3 to regulate immunoglobulin production in B lymphocytes. Cell Death Dis. 2014;5:e1192 pubmed publisher
Magge D, Guo Z, O Malley M, Francis L, Ravindranathan R, Bartlett D. Inhibitors of C5 complement enhance vaccinia virus oncolysis. Cancer Gene Ther. 2013;20:342-50 pubmed publisher
Sun Y, Yu W, Huang L, Hou J, Gong P, Zheng Y, et al. Is asthma related to choroidal neovascularization?. PLoS ONE. 2012;7:e35415 pubmed publisher
Yang Z, Gagarin D, St Laurent G, Hammell N, Toma I, Hu C, et al. Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the interferon-inducible immunoproteasome. Arterioscler Thromb Vasc Biol. 2009;29:1213-9 pubmed publisher

product information

brand :

Tocris

master code :

2585

SKU :

2585/1

product name :

Compstatin

description :

C3-binding peptide; inhibits complement activation

target :

Complement Signaling inhibitors

category :

Peptides

unit size :

1 mg

observed molecular weight :

1550.77

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

Complement inhibitor; binds C3 inhibiting proteolytic cleavage by C3 convertase (IC50 = 28 u M) and activation of classical and alternative complement pathways (IC50 values are 63 and 12 u M respectively). Prolongs graft survival and reduces hyperacute rejection of ex vivo pig kidneys perfused with human blood and inhibits in vivo heparin/protamine-induced complement activation in primates. . Control Peptide also available.

catalog number base :

2585

product keywords :

C3-binding protein inhibits inhibitors complement activation Convertase Complement 2585,

extended description :

C3-binding peptide; inhibits complement activation

formula :

C 66 H 99 N 23 O 17 S 2

formula text :

C66H99N23O17S2

cas num :

206645-99-0

2020 USD :

230

2021 USD :

235 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage