Amlodipine besylate | Tocris Bioscience 2571 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Amlodipine besylate

catalog :

2571

quantity :

50 mg

price :

106 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Sharma D, Tiwari B, Mehto S, Antony C, Kak G, Singh Y, et al. Suppression of Protective Responses upon Activation of L-Type Voltage Gated Calcium Channel in Macrophages during Mycobacterium bovis BCG Infection. PLoS ONE. 2016;11:e0163845 pubmed publisher
Zhong W, Hutchinson T, Chebolu S, Darmani N. Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+/CaMKII-dependent ERK1/2 signaling in the least shrew (Cryptotis parva). PLoS ONE. 2014;9:e104718 pubmed publisher

product information

brand :

Tocris

master code :

2571

SKU :

2571/50

product name :

Amlodipine besylate

description :

CaV1.x blocker

target :

Voltage-gated Calcium Channel Blockers

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

567.05

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC50 = 25 u M).

catalog number base :

2571

product keywords :

Ca2+ channel blockers L-type Calcium CaV Channels L-Type voltage-gated voltage-dependent Norvasc Cav1.x Channels 2571, Voltage-gated calcium channel blocker, voltage gated calcium channel, high-voltage activated Ca2+ channel, high voltage gated ca2+ channel

extended description :

CaV1.x blocker

chemical name text :

2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate

formula :

C 20 H 25 ClN 2 O 5 .C 6 H 6 O 3 S

formula text :

C20H25ClN2O5.C6H6O3S

cas num :

111470-99-6

2020 USD :

102

2021 USD :

106 USD

alt names :

Norvasc

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage