product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
Amlodipine besylate
catalog :
2571/50
quantity :
50 mg
price :
134 USD
more info or order :
citations: 2
Reference
Sharma D, Tiwari B, Mehto S, Antony C, Kak G, Singh Y, et al. Suppression of Protective Responses upon Activation of L-Type Voltage Gated Calcium Channel in Macrophages during Mycobacterium bovis BCG Infection. PLoS ONE. 2016;11:e0163845 pubmed publisher
Zhong W, Hutchinson T, Chebolu S, Darmani N. Serotonin 5-HT3 receptor-mediated vomiting occurs via the activation of Ca2+/CaMKII-dependent ERK1/2 signaling in the least shrew (Cryptotis parva). PLoS ONE. 2014;9:e104718 pubmed publisher
image
image 1 :
Tocris Bioscience 2571/50 image 1
Cat.No. 2571 - Amlodipine besylate C20H25ClN2O5.C6H6O3S CAS No. 111470-99-6
product information
brand :
Tocris
master code :
2571
SKU :
2571/50
product name :
Amlodipine besylate
unit size :
50 mg
seo description :
CaV1.x blocker
target :
Cav1.x Channel Blockers
category :
Small Molecules
purity :
98%
observed molecular weight :
567.05
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Amlodipine besylate is a L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca2+-induced contractions in depolarized rat aorta (IC50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC50 = 25 u M).
top caption :
CaV1.x blocker
extended description :
CaV1.x blocker
chemical name text :
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzenesulfonate
formula :
C20H25ClN2O5.C6H6O3S
formula text :
C20H25ClN2O5.C6H6O3S
cas num :
111470-99-6
USD :
134 USD
product details :
CaV1.x blocker
alt names :
Norvasc
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK