product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
CGP 42112
catalog :
2569
quantity :
1 mg
price :
193 USD
more info or order :
citations: 3
Reference
Raffai G, Lombard J. Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats. J Vasc Res. 2016;53:105-118 pubmed
Nostramo R, Tillinger A, Saavedra J, Kumar A, Pandey V, Serova L, et al. Regulation of angiotensin II type 2 receptor gene expression in the adrenal medulla by acute and repeated immobilization stress. J Endocrinol. 2012;215:291-301 pubmed publisher
Li Y, Xiao D, Dasgupta C, Xiong F, Tong W, Yang S, et al. Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors. Stroke. 2012;43:2483-90 pubmed publisher
product information
brand :
Tocris
master code :
2569
SKU :
2569/1
product name :
CGP 42112
description :
Selective, high affinity AT2 ligand
target :
Additional Angiotensin AT2 Receptor Peptides
category :
Peptides
unit size :
1 mg
observed molecular weight :
1052.2
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=peptides
details of functionality :
Selective, high affinity angiotensin AT2 receptor ligand (Ki = 0.24 nM). Displays agonistic properties at proximal tubule AT2 receptors, causes Na+, K+-ATPase inhibition and sodium excretion. Antagonizes Ang-II induced contractions in rabbit aortic rings (IC50 = 1850 nM).
catalog number base :
2569
product keywords :
Selective high affinity AT2 ligands Receptors Angiotensin CGP42112 Angiotensin AT2 Receptors 2569,
extended description :
Selective, high affinity AT2 ligand
formula :
C 52 H 69 N 13 O 11
formula text :
C52H69N13O11
cas num :
127060-75-7
2020 USD :
187
2021 USD :
193 USD
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK