CGP 42112 | Tocris Bioscience 2569/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CGP 42112

catalog :

2569/1

quantity :

1 mg

price :

216 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Raffai G, Lombard J. Angiotensin-(1-7) Selectively Induces Relaxation and Modulates Endothelium-Dependent Dilation in Mesenteric Arteries of Salt-Fed Rats. J Vasc Res. 2016;53:105-118 pubmed
Wang D, Hu S, Zhu J, Yuan J, Wu J, Zhou A, et al. Angiotensin II type 2 receptor correlates with therapeutic effects of losartan in rats with adjuvant-induced arthritis. J Cell Mol Med. 2013;17:1577-87 pubmed publisher
Nostramo R, Tillinger A, Saavedra J, Kumar A, Pandey V, Serova L, et al. Regulation of angiotensin II type 2 receptor gene expression in the adrenal medulla by acute and repeated immobilization stress. J Endocrinol. 2012;215:291-301 pubmed publisher
Li Y, Xiao D, Dasgupta C, Xiong F, Tong W, Yang S, et al. Perinatal nicotine exposure increases vulnerability of hypoxic-ischemic brain injury in neonatal rats: role of angiotensin II receptors. Stroke. 2012;43:2483-90 pubmed publisher

image

image 1 :

Cat.No. 2569 - CGP 42112 N- -Nicotinoyl-Tyr-Lys-(N- -Z-Arg)-His-Pro-Ile CAS No. 127060-75-7

product information

brand :

Tocris

master code :

2569

SKU :

2569/1

product name :

CGP 42112

unit size :

1 mg

seo description :

Selective, high affinity AT2 ligand

target :

Additional Angiotensin AT2 Receptor Peptides

category :

Peptides

purity :

95%

observed molecular weight :

1052.2

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=peptides

details of functionality :

CGP 42112 is a selective, high affinity angiotensin AT2 receptor ligand (Ki = 0.24 nM). Displays agonistic properties at proximal tubule AT2 receptors, causes Na+, K+-ATPase inhibition and sodium excretion. Antagonizes Ang-II induced contractions in rabbit aortic rings (IC50 = 1850 nM).

top caption :

Selective, high affinity AT2 ligand

extended description :

Selective, high affinity AT2 ligand

formula :

C52H69N13O11

formula text :

C52H69N13O11

cas num :

127060-75-7

USD :

216 USD

product details :

Selective, high affinity AT2 ligand

storage :

Store at -20░C

more info or order :

Tocris Bioscience product webpage