Fexaramine | Tocris Bioscience 2563/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Fexaramine

catalog :

2563/10

quantity :

10 mg (also 50 mg)

price :

259 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Nagiec M, Skepner A, Negri J, Eichhorn M, Kuperwasser N, Comer E, et al. Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression. PLoS ONE. 2015;10:e0120295 pubmed publisher
Cho S, An J, Park H, Yang J, Choi H, Kim S, et al. Positive regulation of osteogenesis by bile acid through FXR. J Bone Miner Res. 2013;28:2109-21 pubmed publisher

image

image 1 :

Cat.No. 2563 - Fexaramine C32H36N2O3 CAS No. 574013-66-4

product information

brand :

Tocris

master code :

2563

SKU :

2563/10

product name :

Fexaramine

unit size :

10 mg (also 50 mg)

seo description :

Potent, selective farnesoid X receptor (FXR) agonist

target :

LXR-like Receptor Agonists

category :

Small Molecules

purity :

97%

observed molecular weight :

496.64

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Fexaramine is a potent, selective farnesoid X receptor agonist (EC50 = 25 nM). Displays no activity at hRXR , hPPAR , hPPAR , hPPAR , mPXR, hPXR, hLXR , hTR , hRAR , mCAR, mERR and hVDR receptors.

top caption :

Potent, selective farnesoid X receptor (FXR) agonist

extended description :

Potent, selective farnesoid X receptor (FXR) agonist

chemical name text :

3-[3-[(Cyclohexylcarbonyl)-[[4 -(dimethylamino)-[1,1 -biphenyl]-4-yl]methyl]amino]phenyl]-2-propenoic acid methyl ester

formula :

C32H36N2O3

formula text :

C32H36N2O3

cas num :

574013-66-4

USD :

259 USD

product details :

Potent, selective farnesoid X receptor (FXR) agonist

storage :

Desiccate at +4░C

more info or order :

Tocris Bioscience product webpage