Calmidazolium chloride | Tocris Bioscience 2561 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Calmidazolium chloride

catalog :

2561

quantity :

10 mg

price :

160 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Kim M, Cho H, Yoon H, Ahn Y, Park E, Jin Y, et al. JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Sci Rep. 2018;8:6611 pubmed publisher
Van Hook M, Parmelee C, Chen M, Cork K, Curto C, Thoreson W. Calmodulin enhances ribbon replenishment and shapes filtering of synaptic transmission by cone photoreceptors. J Gen Physiol. 2014;144:357-78 pubmed publisher
Varadarajan S, Tanaka K, Smalley J, Bampton E, Pellecchia M, Dinsdale D, et al. Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis. PLoS ONE. 2013;8:e56603 pubmed publisher

product information

brand :

Tocris

master code :

2561

SKU :

2561/10

product name :

Calmidazolium chloride

description :

Calmodulin antagonist

target :

Calcium Binding Protein Modulator Antagonists

category :

Small Molecules

unit size :

10 mg

purity :

95%

observed molecular weight :

687.7

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 u M respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.

catalog number base :

2561

product keywords :

Calmodulin antagonists Ca2+ Binding Protein modulators Calcium Signaling Signalling R24571 R 24571 Calcium Binding Protein 2561,

extended description :

Calmodulin antagonist

chemical name text :

1-[Bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride

formula :

C 31 H 23 Cl 7 N 2 O

formula text :

C31H23Cl7N2O

cas num :

57265-65-3

2020 USD :

155

2021 USD :

160 USD

alt names :

R 24571

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage