Calmidazolium chloride | Tocris Bioscience 2561/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Calmidazolium chloride

catalog :

2561/10

quantity :

10 mg

price :

204 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Kim M, Cho H, Yoon H, Ahn Y, Park E, Jin Y, et al. JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway. Sci Rep. 2018;8:6611 pubmed publisher
Van Hook M, Parmelee C, Chen M, Cork K, Curto C, Thoreson W. Calmodulin enhances ribbon replenishment and shapes filtering of synaptic transmission by cone photoreceptors. J Gen Physiol. 2014;144:357-78 pubmed publisher
Varadarajan S, Tanaka K, Smalley J, Bampton E, Pellecchia M, Dinsdale D, et al. Endoplasmic reticulum membrane reorganization is regulated by ionic homeostasis. PLoS ONE. 2013;8:e56603 pubmed publisher

image

image 1 :

Cat.No. 2561 - Calmidazolium chloride C31H23Cl7N2O CAS No. 57265-65-3

product information

brand :

Tocris

master code :

2561

SKU :

2561/10

product name :

Calmidazolium chloride

unit size :

10 mg

seo description :

Calmodulin antagonist

target :

Calcium Binding Protein Modulator Antagonists

category :

Small Molecules

purity :

95%

observed molecular weight :

687.7

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Calmidazolium chloride is a calmodulin antagonist. Inhibits calmodulin-dependent phosphodiesterase and Ca2+-transporting ATPase with IC50 values of 0.15 and 0.35 u M respectively. Also causes elevation of intracellular calcium in HL-60 cells, independent of calmodulin inhibition.

top caption :

Calmodulin antagonist

extended description :

Calmodulin antagonist

chemical name text :

1-[Bis(4-chlorophenyl)methyl]-3-[2-(2,4-dichlorophenyl)-2-(2,4-dichlorobenzyloxy)ethyl]-1H-imidazolium chloride

formula :

C31H23Cl7N2O

formula text :

C31H23Cl7N2O

cas num :

57265-65-3

USD :

204 USD

product details :

Calmodulin antagonist

alt names :

R 24571

storage :

Store at +4░C

more info or order :

Tocris Bioscience product webpage