Ganaxolone | Tocris Bioscience 2531 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Ganaxolone

catalog :

2531

quantity :

10 mg (also 50 mg)

price :

159 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Asiedu M, Mejia G, Ossipov M, Malan T, Kaila K, Price T. Modulation of spinal GABAergic analgesia by inhibition of chloride extrusion capacity in mice. J Pain. 2012;13:546-54 pubmed publisher

product information

brand :

Tocris

master code :

2531

SKU :

2531/10

product name :

Ganaxolone

description :

Potent positive allosteric modulator of GABAA receptors

target :

GABA-A Receptor Modulators

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

332.53

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent positive allosteric modulator of GABAA receptors. Enhances GABA-evoked chloride currents in Xenopus oocytes expressing GABAA receptors (EC50 values are 94, 122 and 213 nM for 2 1 2L, 3 1 2L and 1 1 2L receptors respectively). Exerts anticonvulsive effects in a broad range of animal seizure models.

catalog number base :

2531

product keywords :

Potent positive allosteric modulators GABAA receptors Receptors CCD1042 PAM CCD 1042 GABAA Receptors 2531,

extended description :

Potent positive allosteric modulator of GABAA receptors

chemical name text :

(3 ,5 )-3-Hydroxy-3-methyl-pregnan-20-one

formula :

C 22 H 36 O 2

formula text :

C22H36O2

cas num :

38398-32-2

2020 USD :

155

2021 USD :

159 USD

alt names :

CCD 1042

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage