PPDA | Tocris Bioscience 2530/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

PPDA

catalog :

2530/10

quantity :

10 mg (also 50 mg)

price :

225 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Pan M, Kuo S, Tai C, Liou J, Pei J, Chang C, et al. Neuronal firing patterns outweigh circuitry oscillations in parkinsonian motor control. J Clin Invest. 2016;126:4516-4526 pubmed publisher
Mirante O, Brandalise F, Bohacek J, Mansuy I. Distinct molecular components for thalamic- and cortical-dependent plasticity in the lateral amygdala. Front Mol Neurosci. 2014;7:62 pubmed publisher
Ferando I, Mody I. Altered gamma oscillations during pregnancy through loss of ? subunit-containing GABA(A) receptors on parvalbumin interneurons. Front Neural Circuits. 2013;7:144 pubmed publisher
Carlson S, Kempsell A, Fieber L. Pharmacological evidence that D-aspartate activates a current distinct from ionotropic glutamate receptor currents in Aplysia californica. Brain Behav. 2012;2:391-401 pubmed publisher
Carlson S, Fieber L. Unique ionotropic receptors for D-aspartate are a target for serotonin-induced synaptic plasticity in Aplysia californica. Comp Biochem Physiol C Toxicol Pharmacol. 2012;155:151-9 pubmed publisher

image

image 1 :

Cat.No. 2530 - PPDA C21H18N2O5 CAS No. 684283-16-7

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2530

SKU :

2530/10

product name :

PPDA

Description :

GluN2C/GluN2D-selective NMDA antagonist

target :

NMDA Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

378.38

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

PPDA is a subtype-selective NMDA receptor antagonist that preferentially binds to GluN2C/GluN2D (formally NR2C/NR2D) containing receptors (Ki values are 0.096, 0.125, 0.31 and 0.55 u M for GluN2C, GluN2D, GluN2B and GluN2A subunits respectively). . Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions .

extended description :

GluN2C/GluN2D-selective NMDA antagonist

chemical name text :

(2S*,3R*)-1-(Phenanthren-2-carbonyl)piperazine-2,3-dicarboxylic acid

formula :

C 21 H 18 N 2 O 5

formula text :

C21H18N2O5

cas num :

684283-16-7

USD :

225 USD

product details :

GluN2C/GluN2D-selective NMDA antagonist

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage