YM 26734 | Tocris Bioscience 2522 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

YM 26734

catalog :

2522

quantity :

10 mg

price :

215 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Pernet E, Guillemot L, Burgel P, Martin C, Lambeau G, Sermet Gaudelus I, et al. Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity. Nat Commun. 2014;5:5105 pubmed publisher
di Villa Bianca R, Coletta C, Mitidieri E, De Dominicis G, Rossi A, Sautebin L, et al. Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A2. Br J Pharmacol. 2010;161:1835-42 pubmed publisher

product information

brand :

Tocris

master code :

2522

SKU :

2522/10

product name :

YM 26734

description :

Secretory phospholipase A2 (sPLA2) inhibitor

target :

Phospholipase Inhibitors

category :

Small Molecules

unit size :

10 mg

purity :

95%

observed molecular weight :

730.97

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Competitive inhibitor of secretory phospholipase A2 (sPLA2) that exhibits a broad inhibitory profile to several sPLA2s (IC50 values are 0.2, 1, 1, 1 and 3 u M for sPLA2-X, -IIA, -IID, -V and -IIE respectively). Displays minimal activity at sPLA2-IIF and no activity at cytosolic PLA2, cyclooxygenase and lipoxygenase. Ameliorates local inflammatory responses in TPA-induced mouse ear edema.

catalog number base :

2522

product keywords :

Secretory phospholipases A2 sPLA2 inhibitors inhibits Esterases YM26734 Phospholipases 2522,

extended description :

Secretory phospholipase A2 (sPLA2) inhibitor

chemical name text :

1,1 -[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone

formula :

C 45 H 62 O 8

formula text :

C45H62O8

cas num :

144337-18-8

2020 USD :

210

2021 USD :

215 USD

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage