YM 26734 | Tocris Bioscience 2522/10 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

YM 26734

catalog :

2522/10

quantity :

10 mg

price :

241 USD

citations: 2

Reference
Pernet E, Guillemot L, Burgel P, Martin C, Lambeau G, Sermet Gaudelus I, et al. Pseudomonas aeruginosa eradicates Staphylococcus aureus by manipulating the host immunity. Nat Commun. 2014;5:5105 pubmed publisher
di Villa Bianca R, Coletta C, Mitidieri E, De Dominicis G, Rossi A, Sautebin L, et al. Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A2. Br J Pharmacol. 2010;161:1835-42 pubmed publisher

product information

brand :

Tocris, a Bio-Techne brand

catalog number base :

2522

SKU :

2522/10

product name :

YM 26734

description :

Secretory phospholipase A2 (sPLA2) inhibitor

target :

Phospholipase Inhibitors

unit size :

10 mg

category :

Small Molecules

purity :

95%

storage :

Store at -20°C

observed molecular weight :

730.97

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

YM 26734 is a competitive inhibitor of secretory phospholipase A2 (sPLA2) that exhibits a broad inhibitory profile to several sPLA2s (IC50 values are 0.2, 1, 1, 1 and 3 u M for sPLA2-X, -IIA, -IID, -V and -IIE respectively). Displays minimal activity at sPLA2-IIF and no activity at cytosolic PLA2, cyclooxygenase and lipoxygenase. Ameliorates local inflammatory responses in TPA-induced mouse ear edema.

product keywords :

Secretory phospholipases A2 sPLA2 inhibitors inhibits Esterases YM26734 Phospholipases 2522,

extended description :

Secretory phospholipase A2 (sPLA2) inhibitor

chemical name text :

1,1 -[5-[3,4-Dihydro-7-hydroxy-2-(4-hydroxyphenyl)-2H-1-benzopyran-4-yl]-2,4,6-trihydroxy-1,3-phenylene]bis-1-dodecanone

formula :

C45H62O8

formula text :

C45H62O8

cas num :

144337-18-8

USD :

267

USD 2025 :

241 USD

product details :

Secretory phospholipase A2 (sPLA2) inhibitor