product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
RS 504393
catalog :
2517
quantity :
10 mg
price :
229 USD
more info or order :
citations: 15
Reference |
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Lu W, Tang Y, Zhang Z, Zhang X, Yao Y, Fu C, et al. Inhibiting the mobilization of Ly6C(high) monocytes after acute myocardial infarction enhances the efficiency of mesenchymal stromal cell transplantation and curbs myocardial remodeling. Am J Transl Res. 2015;7:587-97 pubmed
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product information
brand :
Tocris
master code :
2517
SKU :
2517/10
product name :
RS 504393
description :
Highly selective CCR2 chemokine receptor antagonist
target :
Chemokine Receptor Antagonists
category :
Small Molecules
unit size :
10 mg
purity :
99%
observed molecular weight :
417.5
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Extremely selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and 100 u M for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.
catalog number base :
2517
product keywords :
selective CCR2 chemokine receptor antagonists CXCR Chemokine Receptors RS504393 Chemokine CC Receptors 2517,
extended description :
Highly selective CCR2 chemokine receptor antagonist
chemical name text :
6-Methyl-1 -[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4 -piperidin]-2(1H)-one
formula :
C 25 H 27 N 3 O 3
formula text :
C25H27N3O3
cas num :
300816-15-3
2020 USD :
220
2021 USD :
229 USD
storage :
Store at +4°C
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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