Cardamonin | Tocris Bioscience 2509/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Cardamonin

catalog :

2509/10

quantity :

10 mg (also 50 mg)

price :

220 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Kim S, Neuendorff N, Chapkin R, Earnest D. Role of Inflammatory Signaling in the Differential Effects of Saturated and Poly-unsaturated Fatty Acids on Peripheral Circadian Clocks. EBioMedicine. 2016;7:100-11 pubmed publisher
Jia D, Yang W, Li L, Liu H, Tan Y, Ooi S, et al. Î²-Catenin and NF-ÎºB co-activation triggered by TLR3 stimulation facilitates stem cell-like phenotypes in breast cancer. Cell Death Differ. 2015;22:298-310 pubmed publisher
Yadav V, Prasad S, Aggarwal B. Cardamonin sensitizes tumour cells to TRAIL through ROS- and CHOP-mediated up-regulation of death receptors and down-regulation of survival proteins. Br J Pharmacol. 2012;165:741-53 pubmed publisher

image

image 1 :

Cat.No. 2509 - Cardamonin C16H14O4 CAS No. 19309-14-9

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2509

SKU :

2509/10

product name :

Cardamonin

Description :

Inhibitor of NF- B activation; anti-inflammatory

target :

NFkB/IkB Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

270.28

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Cardamonin is a chalone analog that display anti-inflammatory activity. Inhibits NO and PGE2 production from LPS- and IFN- -induced RAW cells and inhibits TXB2 production via the COX-1 and COX-2 pathways. Inhibits NF- B activation via inhibition of I B degradation and phosphorylation, I B kinase activation and NF- B nuclear translocation.

extended description :

Inhibitor of NF- B activation; anti-inflammatory

chemical name text :

(2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one

formula :

C 16 H 14 O 4

formula text :

C16H14O4

cas num :

19309-14-9

USD :

220 USD

product details :

Inhibitor of NF- B activation; anti-inflammatory

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage