MRS 2693 trisodium salt | Tocris Bioscience 2502/1 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

MRS 2693 trisodium salt

catalog :

2502/1

quantity :

1 mg

price :

399 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Moreira Souza A, Marinho Y, Corrêa G, Santoro G, Coutinho C, Vommaro R, et al. Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages. PLoS ONE. 2015;10:e0133502 pubmed publisher
Obba S, Hizir Z, Boyer L, Selimoglu Buet D, Pfeifer A, Michel G, et al. The PRKAA1/AMPKÎ±1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML. Autophagy. 2015;11:1114-29 pubmed publisher
Yu W, Sun X, Robson S, Hill W. Extracellular UDP enhances P2X-mediated bladder smooth muscle contractility via P2Y(6) activation of the phospholipase C/inositol trisphosphate pathway. FASEB J. 2013;27:1895-903 pubmed publisher
Matsumoto T, Tostes R, Webb R. Uridine adenosine tetraphosphate-induced contraction is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats. Am J Physiol Heart Circ Physiol. 2011;301:H409-17 pubmed publisher

image

image 1 :

Cat.No. 2502 - MRS 2693 trisodium salt C9H10IN2Na3O12P2 CAS No. 1448858-83-0

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2502

SKU :

2502/1

product name :

MRS 2693 trisodium salt

Description :

Selective P2Y6 agonist

target :

P2Y Receptor Agonists

category :

Small Molecules

unit size :

1 mg

purity :

95%

observed molecular weight :

596

url print :

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details of functionality :

MRS 2693 trisodium salt is a selective P2Y6 agonist (EC50 = 0.015 M at the hP2Y6 receptor). Displays no activity at other P2Y subtypes. Exerts a cytoprotective effect in an in vivo mouse model of hindlimb skeletal muscle ischemia/reperfusion injury.

extended description :

Selective P2Y6 agonist

chemical name text :

5-Iodouridine-5 -O-diphosphate trisodium salt

formula :

C 9 H 10 IN 2 Na 3 O 12 P 2

formula text :

C9H10IN2Na3O12P2

cas num :

1448858-83-0

USD :

399 USD

product details :

Selective P2Y6 agonist

alt names :

5-Iodo-UDP trisodium salt

storage :

Store at -20°C

more info or order :

Tocris Bioscience product webpage