ZM 306416 hydrochloride | Tocris Bioscience 2499 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ZM 306416 hydrochloride

catalog :

2499

quantity :

1 mg (also 10 mg)

price :

91 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Marino S, Bishop R, Capulli M, Sophocleous A, Logan J, Mollat P, et al. Regulation of breast cancer induced bone disease by cancer-specific IKKβ. Oncotarget. 2018;9:16134-16148 pubmed publisher
Zhang C, Ellis J, Yin C. Inhibition of vascular endothelial growth factor signaling facilitates liver repair from acute ethanol-induced injury in zebrafish. Dis Model Mech. 2016;9:1383-1396 pubmed
Crouch E, Liu C, Silva Vargas V, Doetsch F. Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage. J Neurosci. 2015;35:4528-39 pubmed publisher
Lee Y, Manegold J, Kim A, Pouget C, Stachura D, Clements W, et al. FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nat Commun. 2014;5:5583 pubmed publisher
Yuan X, Eng G, Arkonac D, Chao P, Vunjak Novakovic G. Endothelial cells enhance the migration of bovine meniscus cells. Arthritis Rheumatol. 2015;67:182-92 pubmed publisher

product information

brand :

Tocris

master code :

2499

SKU :

2499/1

product name :

ZM 306416 hydrochloride

description :

Inhibitor of VEGF receptor tyrosine kinase

target :

VEGF Receptor Inhibitors

category :

Small Molecules

unit size :

1 mg (also 10 mg)

purity :

99%

observed molecular weight :

370.21

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 u M respectively) and displays 3-fold selectivity over FGFR-1. Orally active in vivo .

catalog number base :

2499

product keywords :

inhibitors inhibits receptors tyrosine kinase VEGFR Vascular Endothelial Growth Factor Receptors KDR Flt RTKs ZM306416 hydrochloride AstraZeneca VEGFR 2499, VEGFR, VEGF R

extended description :

Inhibitor of VEGF receptor tyrosine kinase

chemical name text :

4-[(4 -Chloro-2 -fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride

formula :

C 16 H 13 N 3 O 2 FCl.HCl

formula text :

C16H13N3O2FCl.HCl

cas num :

196603-47-1

2020 USD :

101

2021 USD :

91 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage