This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Tocris Bioscience
product type :
chemical
product name :
ZM 306416 hydrochloride
catalog :
2499/1
quantity :
1 mg (also 10 mg)
price :
91 USD
citations: 5
Reference
Marino S, Bishop R, Capulli M, Sophocleous A, Logan J, Mollat P, et al. Regulation of breast cancer induced bone disease by cancer-specific IKKβ. Oncotarget. 2018;9:16134-16148 pubmed publisher
Zhang C, Ellis J, Yin C. Inhibition of vascular endothelial growth factor signaling facilitates liver repair from acute ethanol-induced injury in zebrafish. Dis Model Mech. 2016;9:1383-1396 pubmed
Crouch E, Liu C, Silva Vargas V, Doetsch F. Regional and stage-specific effects of prospectively purified vascular cells on the adult V-SVZ neural stem cell lineage. J Neurosci. 2015;35:4528-39 pubmed publisher
Lee Y, Manegold J, Kim A, Pouget C, Stachura D, Clements W, et al. FGF signalling specifies haematopoietic stem cells through its regulation of somitic Notch signalling. Nat Commun. 2014;5:5583 pubmed publisher
Yuan X, Eng G, Arkonac D, Chao P, Vunjak Novakovic G. Endothelial cells enhance the migration of bovine meniscus cells. Arthritis Rheumatol. 2015;67:182-92 pubmed publisher
product information
brand :
Tocris
SKU :
2499/1
product name :
ZM 306416 hydrochloride
unit sizes :
1 mg (also 10 mg)
description :
Inhibitor of VEGF receptor tyrosine kinase
target :
VEGF Receptor Inhibitors
category :
Small Molecules
purity :
99%
storage :
Desiccate at RT
observed molecular weight :
370.21
url print :
?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 u M respectively) and displays 3-fold selectivity over FGFR-1. Orally active in vivo .
catalog number base :
2499
extended description :
Inhibitor of VEGF receptor tyrosine kinase
chemical name text :
4-[(4 -Chloro-2 -fluoro)phenylamino]-6,7-dimethoxyquinazoline hydrochloride
formula :
C 16 H 13 N 3 O 2 FCl.HCl
formula text :
C16H13N3O2FCl.HCl
cas num :
196603-47-1
USD :
91 USD
default size :
TRUE
product details :
Inhibitor of VEGF receptor tyrosine kinase
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK