Xaliproden hydrochloride | Tocris Bioscience 2491 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Xaliproden hydrochloride

catalog :

2491

quantity :

10 mg (also 50 mg)

price :

167 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed publisher

product information

brand :

Tocris

master code :

2491

SKU :

2491/10

product name :

Xaliproden hydrochloride

description :

High affinity 5-HT1A agonist; orally active

target :

5-HT1 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

417.9

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Orally active, full agonist at 5-HT1A receptors. Binds rat 5-HT1A with high affinity (Ki = 2.0 nM) and is 300-fold selective over other 5-HT receptor subtypes (IC50 650 nM). Increases motoneuron survival and promotes effects of NGF on neurite outgrowth in vitro . Displays neurotrophic activity in several neurodegenerative models in vivo .

catalog number base :

2491

product keywords :

Orally active high affinity 5-HT1A agonists Serotonin Receptors SR57746A SR 57746A 5-HT1A Receptors 2491,

extended description :

High affinity 5-HT1A agonist; orally active

chemical name text :

1,2,3,6-Tetrahydro-1-[2-(2-naphthalenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-pyridine hydrochloride

formula :

C 24 H 22 F 3 N.HCl

formula text :

C24H22F3N.HCl

cas num :

90494-79-4

2020 USD :

163

2021 USD :

167 USD

alt names :

SR 57746A

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage