Proxyfan oxalate | Tocris Bioscience 2477 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Proxyfan oxalate

catalog :

2477

quantity :

10 mg (also 50 mg)

price :

122 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Singh J, Maniyar R, Shirsath V. Development of time-resolved fluorescent based [EU]-GTP binding assay for selection of human Histamine 3 receptor antagonists/inverse agonist: a potential target for Alzheimer's treatment. Ann Neurosci. 2012;19:71-5 pubmed publisher

product information

brand :

Tocris

master code :

2477

SKU :

2477/10

product name :

Proxyfan oxalate

description :

High affinity H3 ligand

target :

Histamine H3 Receptor Agonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

306.32

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

High affinity histamine H3 receptor ligand (pKi = 8.62) that acts as a protean agonist at recombinant and native receptors. In functional studies, activity ranges from full agonist to inverse agonist depending on system used. Displays partial agonist effects on cAMP inhibition and MAPK activity, neutral antagonist activity on histamine release and partial inverse agonism of [3H]-arachidonic acid release.

catalog number base :

2477

product keywords :

High affinity H3 ligands Receptors Histamine histaminergic Histamine H3 Receptors 2477,

extended description :

High affinity H3 ligand

chemical name text :

4-[3-(Phenylmethoxy)propyl]-1H-imidazole oxalate

formula :

C 13 H 16 N 2 O.C 2 H 2 O 4

formula text :

C13H16N2O.C2H2O4

cas num :

1620017-81-3

2020 USD :

135

2021 USD :

122 USD

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage