ER 27319 maleate | Tocris Bioscience 2471/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ER 27319 maleate

catalog :

2471/10

quantity :

10 mg (also 50 mg)

price :

199 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Tóth A, Zajta E, Csonka K, Vagvolgyi C, Netea M, Gacser A. Specific pathways mediating inflammasome activation by Candida parapsilosis. Sci Rep. 2017;7:43129 pubmed publisher
Rycaj K, Cho E, Liu X, Chao H, Liu B, Li Q, et al. Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells. Oncotarget. 2016;7:14220-40 pubmed publisher
Ng G, Sharma K, Ward S, Desrosiers M, Stephens L, Schoel W, et al. Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. Immunity. 2008;29:807-18 pubmed publisher

image

image 1 :

Cat.No. 2471 - ER 27319 maleate C18H20N2O.C4H4O4 CAS No. 1204480-26-1

product information

brand :

Tocris

catalog number base :

2471

SKU :

2471/10

product name :

ER 27319 maleate

units size :

10 mg (also 50 mg)

description :

Selective Syk kinase inhibitor

target :

Syk Kinase Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

396.17

url print :

?utm_source=biocompare&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

review stars :

details of functionality :

ER 27319 maleate is a selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- production (IC50 = 10 u M) and other related signaling events.

top caption :

Selective Syk kinase inhibitor

extended description :

Selective Syk kinase inhibitor

chemical name text :

10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate

formula :

C18H20N2O.C4H4O4

formula text :

C18H20N2O.C4H4O4

cas num :

1204480-26-1

USD :

199 USD

product details :

Selective Syk kinase inhibitor

storage :

Desiccate at +4Â°C

more info or order :

Tocris Bioscience product webpage