ER 27319 maleate | Tocris Bioscience 2471/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

ER 27319 maleate

catalog :

2471/10

quantity :

10 mg (also 50 mg)

price :

197 USD

more info or order :

Tocris Bioscience product webpage

citations: 2

Reference
Rycaj K, Cho E, Liu X, Chao H, Liu B, Li Q, et al. Longitudinal tracking of subpopulation dynamics and molecular changes during LNCaP cell castration and identification of inhibitors that could target the PSA-/lo castration-resistant cells. Oncotarget. 2016;7:14220-40 pubmed publisher
Ng G, Sharma K, Ward S, Desrosiers M, Stephens L, Schoel W, et al. Receptor-independent, direct membrane binding leads to cell-surface lipid sorting and Syk kinase activation in dendritic cells. Immunity. 2008;29:807-18 pubmed publisher

image

image 1 :

Cat.No. 2471 - ER 27319 maleate C18H20N2O.C4H4O4 CAS No. 1204480-26-1

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2471

SKU :

2471/10

product name :

ER 27319 maleate

Description :

Selective Syk kinase inhibitor

target :

Syk Kinase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

396.17

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

ER 27319 maleate is a selective inhibitor of Syk kinase. Inhibits tyrosine phosphorylation of Syk initiated by the engagement of Fc RI in rat and human mast cells. Results in the abrogation of degranulation, TNF- production (IC50 = 10 u M) and other related signaling events.

extended description :

Selective Syk kinase inhibitor

chemical name text :

10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate

formula :

C 18 H 20 N 2 O.C 4 H 4 O 4

formula text :

C18H20N2O.C4H4O4

cas num :

1204480-26-1

USD :

197 USD

product details :

Selective Syk kinase inhibitor

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage