Nimesulide | Tocris Bioscience 2470 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Nimesulide

catalog :

2470

quantity :

100 mg

price :

48 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Baranowska Kuczko M, Kozłowska H, Kozłowski M, Schlicker E, Kloza M, Surazynski A, et al. Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. Naunyn Schmiedebergs Arch Pharmacol. 2014;387:477-86 pubmed publisher
Anneken J, Cunningham J, Collins S, Yamamoto B, Gudelsky G. MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase. J Neuroimmune Pharmacol. 2013;8:58-65 pubmed publisher
Staniaszek L, Norris L, Kendall D, Barrett D, Chapman V. Effects of COX-2 inhibition on spinal nociception: the role of endocannabinoids. Br J Pharmacol. 2010;160:669-76 pubmed publisher

product information

brand :

Tocris

master code :

2470

SKU :

2470/100

product name :

Nimesulide

description :

Cyclooxygenase-2 (COX-2) inhibitor

target :

Cyclooxygenase Inhibitors

category :

Small Molecules

unit size :

100 mg

purity :

99%

observed molecular weight :

308.31

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Selective, orally active cyclooxygenase-2 (COX-2) inhibitor. Produces potent analgesic, anti-inflammatory and antipyretic activities in vivo . Reported to produce fewer gastrointestinal side effects than standard NSAIDs. Also inhibits sodium-dependent neutral amino acid transporter B0AT1 (SLC6A19; IC50 = 23 M).

catalog number base :

2470

product keywords :

Cyclooxygenase-2 COX-2 inhibitors inhibits Cyclooxygenase Oxygenases Oxidases B0AT1 SLC6A19 sodium-dependent neutral amino acid transporter Flogovital Aulin Cyclooxygenase Other Ion Pumps/Transporters 2470,

extended description :

Cyclooxygenase-2 (COX-2) inhibitor

chemical name text :

N-(4-Nitro-2-phenoxyphenyl)methanesulfonamide

formula :

C 13 H 12 N 2 O 5 S

formula text :

C13H12N2O5S

cas num :

51803-78-2

2020 USD :

2021 USD :

48 USD

alt names :

Flogovital, Aulin

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage