Tropisetron hydrochloride | Tocris Bioscience 2459/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Tropisetron hydrochloride

catalog :

2459/10

quantity :

10 mg (also 50 mg)

price :

201 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Otvos R, Iyer J, van Elk R, Ulens C, Niessen W, Somsen G, et al. Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Toxins (Basel). 2015;7:2336-53 pubmed publisher
Johnson S, Krisp A, Bartman M. Hypoxia switches episodic breathing to singlet breathing in red-eared slider turtles (Trachemys scripta) via a tropisetron-sensitive mechanism. Respir Physiol Neurobiol. 2015;207:48-57 pubmed publisher
Sendin G, Bourien J, Rassendren F, Puel J, Nouvian R. Spatiotemporal pattern of action potential firing in developing inner hair cells of the mouse cochlea. Proc Natl Acad Sci U S A. 2014;111:1999-2004 pubmed publisher
Spilman P, Descamps O, Gorostiza O, Peters Libeu C, Poksay K, Matalis A, et al. The multi-functional drug tropisetron binds APP and normalizes cognition in a murine Alzheimer's model. Brain Res. 2014;1551:25-44 pubmed publisher

image

image 1 :

Cat.No. 2459 - Tropisetron hydrochloride C17H20N2O2.HCl CAS No. 105826-92-4

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2459

SKU :

2459/10

product name :

Tropisetron hydrochloride

Description :

Potent 5-HT3 antagonist; also 7 nAChR partial agonist

target :

5-HT3 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

320.82

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Tropisetron hydrochloride is a potent, orally active 5-HT3 receptor antagonist. Antiemetic. Also partial agonist of 7 nAChR. Activates 7Q79G-GlyR chimeric ion channels (EC50 = 38 nM)

extended description :

Potent 5-HT3 antagonist; also 7 nAChR partial agonist

chemical name text :

(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylic acid ester monohydrochloride

formula :

C 17 H 20 N 2 O 2 .HCl

formula text :

C17H20N2O2.HCl

cas num :

105826-92-4

USD :

201 USD

product details :

Potent 5-HT3 antagonist; also 7 nAChR partial agonist

alt names :

Novaban, ICS 205930

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage