LY 2183240 | Tocris Bioscience 2452 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

LY 2183240

catalog :

2452

quantity :

1 mg (also 10 mg)

price :

112 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Gonzalez Islas C, Garcia Bereguiain M, Wenner P. Tonic and transient endocannabinoid regulation of AMPAergic miniature postsynaptic currents and homeostatic plasticity in embryonic motor networks. J Neurosci. 2012;32:13597-607 pubmed

product information

brand :

Tocris

master code :

2452

SKU :

2452/1

product name :

LY 2183240

description :

Highly potent anandamide uptake inhibitor; also inhibits FAAH

target :

Cannabinoid Transporter Inhibitors

category :

Small Molecules

unit size :

1 mg (also 10 mg)

purity :

98%

observed molecular weight :

307.35

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Novel and highly potent blocker of anandamide uptake (IC50 = 270 pM). Inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). Following i.p. administration in rats, increases brain anandamide concentration and exerts antinociceptive effects in formalin model of pain.

catalog number base :

2452

product keywords :

FAAH inhibitors inhibits anandamide reuptake potent Anandamide Amidase Fatty Acid Amide Hydrolases AMT Transporters cannabinoids Monoamine Neurotransmitter LY2183240 Cannabinoid Transporters Fatty Acid Amide Hydrolase (FAAH) Other Cannabinoids 2452,

extended description :

Highly potent anandamide uptake inhibitor; also inhibits FAAH

chemical name text :

5-[(1,1 -Biphenyl]-4-yl)methyl]-N,N-dimethyl-1H-tetrazole-1-carboxamide

formula :

C 17 H 17 N 5 O

formula text :

C17H17N5O

cas num :

874902-19-9

2020 USD :

108

2021 USD :

112 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage