AC 55649 | Tocris Bioscience 2436 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AC 55649

catalog :

2436

quantity :

50 mg

price :

593 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
Lee J, Protze S, Laksman Z, Backx P, Keller G. Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations. Cell Stem Cell. 2017;21:179-194.e4 pubmed publisher
Shrestha R, Conti D, Tamura N, Braun D, Ramalingam R, Cieśliński K, et al. Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells. Nat Commun. 2017;8:150 pubmed publisher
Kelley M, Phomakay R, Lee M, Niedzwiedz V, Mayo R. Retinoic acid receptor gamma impacts cellular adhesion, Alpha5Beta1 integrin expression and proliferation in K562 cells. PLoS ONE. 2017;12:e0178116 pubmed publisher
Kang S, Park J, Cho J, Ulrich B, Kim C. Complementary roles of retinoic acid and TGF-?1 in coordinated expression of mucosal integrins by T cells. Mucosal Immunol. 2011;4:66-82 pubmed publisher
Tay S, Dickmann L, Dixit V, Isoherranen N. A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation. Mol Pharmacol. 2010;77:218-27 pubmed publisher

product information

brand :

Tocris

master code :

2436

SKU :

2436/50

product name :

AC 55649

description :

Selective RAR 2 agonist

target :

Retinoic Acid Receptor Agonists

category :

Small Molecules

unit size :

50 mg

purity :

99%

observed molecular weight :

310.44

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent, isoform-selective RAR 2 receptor agonist (pEC50 values are 6.9, 5.7 and 5.6 at RAR 2, RAR 1 and RAR respectively) that displays 100-fold selectivity versus other retinoid receptors. Inhibits proliferation of the breast cancer cell line MCF-7.

catalog number base :

2436

product keywords :

Selective RAR RARbeta2 agonists RAMBA Retinoic Acid Receptors AC55649 Retinoic Acid Receptors 2436,

extended description :

Selective RAR 2 agonist

chemical name text :

4 -Octyl-[1,1 -biphenyl]-4-carboxylic acid

formula :

C 21 H 26 O 2

formula text :

C21H26O2

cas num :

59662-49-6

2020 USD :

581

2021 USD :

593 USD

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage