CCT 018159 | Tocris Bioscience 2435/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

CCT 018159

catalog :

2435/10

quantity :

10 mg (also 50 mg)

price :

211 USD

more info or order :

Tocris Bioscience product webpage

image

image 1 :

Cat.No. 2435 - CCT 018159 C20H20N2O4 CAS No. 171009-07-7

product information

brand :

Tocris, a Bio-Techne Brand

catalog number base :

2435

SKU :

2435/10

product name :

CCT 018159

Description :

Hsp90 inhibitor

target :

HSP90 Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

352.39

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CCT 018159 is a novel inhibitor of heat shock protein 90 (Hsp90) ATPase activity (IC50 = 5.7 u M) that displays selectivity over human Hsp72 and topoisomerase II. Inhibits proliferation of HCT116 human colon tumor cells and produces upregulation of Hsp70 and downregulation of c-Raf and cdk4. More soluble than 17-AAG (Cat. No. 1515) and is independent of NQO1/DT-diaphorase and P-glycoprotein expression.

extended description :

Hsp90 inhibitor

chemical name text :

4-[4-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-methyl-1H-pyrazol-3-yl]-6-ethyl-1,3-benzenediol

formula :

C 20 H 20 N 2 O 4

formula text :

C20H20N2O4

cas num :

171009-07-7

USD :

211 USD

product details :

Hsp90 inhibitor

storage :

Store at +4°C

more info or order :

Tocris Bioscience product webpage